| 主要業績 |
- Inomata Y, Kawatani N, Yamashita H, Hattori F.: Lgr6-expressing functional nail stem-like cells differentiated from human-induced pluripotent stem cells. PLOS ONE 2024;19(5) e0303260. [Link] プレスリリース、
日本経済新聞および産経新聞、他9紙に掲載されました。
- Bando K, Yamashita H, Hattori F.: An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells. J. Vis. Exp. 2024;Jan 26:(202). [Link]
- Yamashita H, Hattori F.: Application of Live Mitochondria Staining in Cell-Sorting to Purify Hepatocytes Derived from Human Induced Pluripotent Stem Cells. J. Vis. Exp. 2023;Dec 1:(202). [Link]
- Hanafusa Y, Shiraishi A, Hattori F.:Machine learning discriminates P2X7-mediated intracellular calcium sparks in human-induced pluripotent stem cell-derived neural stem cells. Sci Rep 2023;13:12673. [Link]
プレスリリース、
日経バイオテクでの紹介はこちら
- Bando K, Yamashita H, Hattori F.: An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells. J. Vis. Exp. 2024;Jan 26:(202). [Link]
- Hattori F.: A Novel Cell Injection Method with Minimum Invasion. J. Vis. Exp. 2023;Apr 21:(194). [Link]
- Nishimoto R, Kodama C, Yamashita H, Hattori F.: Human-induced pluripotent stem cell-derived keratinocyte-like cells for research on protease-activated receptor 2 in non-histaminergic cascades of atopic dermatitis. J. Pharmacol. Exp. Ther. 2022;384:248-253. [Link]
Viewpoint articleとして取り上げられました。Viewpoint Awardを受賞
- Bando K, Yamashita H, Tsumori M, Minoura H, Okumura K, Hattori F.: Compact automated culture machine for human induced pluripotent stem cell maintenance and differentiation. Front. Bioeng. Biotechnol. 2022;10:1074990.[Link]
- Ito A, Okada T, Minato N, Hattori F.: Possible internal viral shedding and interferon production after clinical recovery from COVID-19: Case report. Frontiers of medicine 2022;9:959196.[Link]
- 総説:山下裕美, 服部文幸.: ミトコンドリア量とALCAMの組み合わせによるヒト多能性幹細胞由来肝細胞の精製法. 月刊 細胞 2021;53(11):58.[Link]
- Higashikuse Y, Mittal N, Arimura T, Yoon SH, Oda M, Enomoto H, Kaneda R, Hattori F, Suzuki T, Kawakami A, Gasch A, Furukawa T, Labeit S, Fukuda K, Kimura A, Makino S.: Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients.Dis Model Mech 2019;12(11):dmm041103.[Link]
- Yamashita H, Fukuda K, Hattori F. Hepatocyte-like cells derived from human pluripotent stem cells can be enriched by combination of mitochondrial content and activated leukocyte cell adhesion molecule.JMA Journal, 2019: 2(2); 174-183 [Link].
- Park SH, Uzawa T, Hattori F, Ogino S, Morimoto N, Tsuneda S, Ito Y. "All-in-one" in vitro selection of collagen-binding vascular endothelial growth factor.Biomaterials 2018 Apr;161:270-278.
- Tohyama S, Fujita J, Hishiki T, Matsuura T, Hattori F, Ohno R, Kanazawa H, Seki T, Nakajima K, Kishino Y, Okada M, Hirano A, Kuroda T, Yasuda S, Sato Y, Yuasa S, Sano M, Suematsu M, Fukuda K. Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells. Cell Metabolism 2016 Apr 12;23(4):663-74.
- Hashimoto H, Yuasa S, Tabata H, Tohyama S, Seki T, Egashira T, Hayashiji N, Hattori F, Kusumoto D, Kunitomi A, Takei M, Kashimura S, Yozu G, Shimojima M, Motoda C, Muraoka N, Nakajima K, Sakaue-Sawano A, Miyawaki A, Fukuda K. Analysis of cardiomyocyte movement in the developing murine heart. Biochemical and Biophysical Research Communications. 2015 Sep 4;464(4):1000-7.
- Hemmi N, Tohyama S, Nakajima K, Kanazawa H, Suzuki T, Hattori F, Seki T, Kishino Y, Hirano A, Okada M, Tabei R, Ohno R, Fujita C, Haruna T, Yuasa S, Sano M, Fujita J, Fukuda K. A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes. Stem Cells Translational Medicine 2014 Dec;3(12):1473-83.
- Hashimoto H, Yuasa S, Tabata H, Tohyama S, Hayashiji N, Hattori F, Muraoka N, Egashira T, Okata S, Yae K, Seki T, Nishiyama T, Nakajima K, Sakaue-Sawano A, Miyawaki A, Fukuda K. Time-lapse imaging of cell cycle dynamics during development in living cardiomyocyte. Journal of Molecular Cell Cardiology 2014 Jul;72:241-9.
- Ohno Y, Yuasa S, Egashira T, Seki T, Hashimoto H, Tohyama S, Saito Y, Kunitomi A, Shimoji K, Onizuka T, Kageyama T, Yae K, Tanaka T, Kaneda R, Hattori F, Murata M, Kimura K, Fukuda K. Distinct iPS Cells Show Different Cardiac Differentiation Efficiency. Stem Cells International 2013;2013:659739.
- Tohyama S, Hattori F, Sano M, Hishiki T, Nagahata Y, Matsuura T, Hashimoto H, Suzuki T, Yamashita H, Satoh Y, Egashira T, Seki T, Muraoka N, Yamakawa H, Ohgino Y, Tanaka T, Yoichi M, Yuasa S, Murata M, Suematsu M, Fukuda K. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell 2013 Jan 3;12(1):127-37.
- Egashira T, Yuasa S, Suzuki T, Aizawa Y, Yamakawa H, Matsuhashi T, Ohno Y, Tohyama S, Okata S, Seki T, Kuroda Y, Yae K, Hashimoto H, Tanaka T, Hattori F, Sato T, Miyoshi S, Takatsuki S, Murata M, Kurokawa J, Furukawa T, Makita N, Aiba T, Shimizu W, Horie M, Kamiya K, Kodama I, Ogawa S, Fukuda K. Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovascular Research 2012 Sep 1;95(4):419-29.
- Hattori F. Review: Extracellular cyclophilin A as a humoral factor modulating cardiovascular inflammatory responses. Journal of Molecular Cell Cardiology 2012 Jul;53(1):1-2.
- Hattori F, Fukuda K. Review: Strategies for replacing myocytes with induced pluripotent stem in clinical protocols. Transplantation Reviews (Orlando). 2012 Jul;26(3):223-32.
- Tajima H, Imada K, Sakuma M, Hattori F, Nara T, Kamo N, Homma M, Kawagishi I. Ligand specificity determined by differentially arranged common ligand-binding residues in bacterial amino acid chemoreceptors Tsr and Tar. Journal of Biological Chemistry 2011 Dec 9;286(49):42200-10.
- Li W, Yamashita H, Hattori F, Chen H, Tohyama S, Satoh Y, Sasaki E, Yuasa S, Makino S, Sano M, Fukuda K. Simple autogeneic feeder cell preparation for pluripotent stem cells. Stem Cell Research 2011 Jan;6(1):83-9.
- Hara M, Yuasa S, Shimoji K, Onizuka T, Hayashiji N, Ohno Y, Arai T, Hattori F, Kaneda R, Kimura K, Makino S, Sano M, Fukuda K. G-CSF influences mouse skeletal muscle development and regeneration by stimulating myoblast proliferation. Journal of Experimental Medicine 2011 Apr 11;208(4):715-27.
- Hattori F. Review: CD117, adult cardiac stem cell marker, is transiently expressed in methothelial epicardial cells. Journal of Molecular Cell Cardiology 2010 Nov;49(5):711-2.
- Yuasa S, Onizuka T, Shimoji K, Ohno Y, Kageyama T, Yoon SH, Egashira T, Seki T, Hashimoto H, Nishiyama T, Kaneda R, Murata M, Hattori F, Makino S, Sano M, Ogawa S, Prall OW, Harvey RP, Fukuda K. Zac1 is an essential transcription factor for cardiac morphogenesis. Circulation Research 2010 Apr 2;106(6):1083-91
- Hattori F, Fukuda K. Review: Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium. Experimental Molecular Medicine. 2010 Mar 31;42(3):155-65.
- Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, Ohno Y, Chen H, Egasgira T, Seki T, Yae K, Koshimizu U, Ogawa S, Fukuda K. G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell 2010 Mar 5;6(3):227-37.
- Hattori F, Chen H, Yamashita H, Tohyama S, Satoh YS, Yuasa S, Li W, Yamakawa H, Tanaka T, Onitsuka T, Shimoji K, Ohno Y, Egashira T, Kaneda R, Murata M, Hidaka K, Morisaki T, Sasaki E, Suzuki T, Sano M, Makino S, Oikawa S, Fukuda K. Nongenetic method for purifying stem cell-derived cardiomyocytes. Nature Methods 2010 Jan;7(1):61-6.
- Endo J, Sano M, Katayama T, Hishiki T, Shinmura K, Morizane S, Matsuhashi T, Katsumata Y, Zhang Y, Ito H, Nagahata Y, Marchitti S, Nishimaki K, Wolf AM, Nakanishi H, Hattori F, Vasiliou V, Adachi T, Ohsawa I, Taguchi R, Hirabayashi Y, Ohta S, Suematsu M, Ogawa S, Fukuda K.Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart. Circulation Research 2009 Nov 20;105(11):1118-27.
- Suzuki R, Hattori F, Itabashi Y, Yoshioka M, Yuasa S, Manabe-Kawaguchi H, Murata M, Makino S, Kokaji K, Yozu R, Fukuda K. Omentopexy enhances graft function in myocardial cell sheet transplantation. Biochemical and Biophysical Research Communications 2009 Sep 18;387(2):353-9.
- Tanaka T, Tohyama S, Murata M, Nomura F, Kaneko T, Chen H, Hattori F, Egashira T, Seki T, Ohno Y, Koshimizu U, Yuasa S, Ogawa S, Yamanaka S, Yasuda K, Fukuda K. In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochemical and Biophysical Research Communications 2009 Aug 7;385(4):497-502.
- Chen H, Hattori F, Murata M, Li W, Yuasa S, Onizuka T, Shimoji K, Ohno Y,Sasaki E, Kimura K, Hakuno D, Sano M, Makino S, Ogawa S, Fukuda K. Common marmoset embryonic stem cell can differentiate into cardiomyocytes. Biochemical and Biophysical Research Communications 2008 May 9;369(3):801-6.
- Ieda M, Kanazawa H, Kimura K, Hattori F, Ieda Y, Taniguchi M, Lee JK, Matsumura K, Tomita Y, Miyoshi S, Shimoda K, Makino S, Sano M, Kodama I, Ogawa S, Fukuda K. Sema3a maintains normal heart rhythm through sympathetic innervation patterning. Nature Medicine 2007 May;13(5):604-12.
- Hattori F, Oikawa S. Peroxiredoxins in the central nervous system. Review: Subcellular Biochemistry 2007;44:357-74.
- Nagaoka M, Koshimizu U, Yuasa S, Hattori F, Chen H, Tanaka T, Okabe M, Fukuda K, Akaike T. E-cadherin-coated plates maintain pluripotent ES cells without colony formation. PLoS One 2006 Dec 20;1:e15.
- Matsushima S, Ide T, Yamato M, Matsusaka H, Hattori F, Ikeuchi M, Kubota T, Sunagawa K, Hasegawa Y, Kurihara T, Oikawa S, Kinugawa S, Tsutsui H. Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 2006 Apr 11;113(14):1779-86.
- Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, Kinoshita M, Hattori F, Fukami S, Shimazaki T, Ogawa S, Okano H, Fukuda K. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nature Biotechnology. 2005 May;23(5):607-11.
- Hattori F, Murayama N, Noshita T, Oikawa S. Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. Journal of Neurochemistry 2003 Aug;86(4):860-8.
- Kamei R, Kitagawa Y, Kadokura M, Hattori F, Hazeki O, Ebina Y, Nishihara T, Oikawa S. Shikonin stimulates glucose uptake in 3T3-L1 adipocytes via an insulin-independent tyrosine kinase pathway. Biochemcal and Biophysical Research Communications 2002 Apr 5;292(3):642-51.
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