| 主要業績 |
- Okano M, Yasuda M, Shimomura Y, Matsuoka Y, Shirouzu Y, Fujioka T, Kyo M, Tsuji S, Kaneko K, Hitomi H,: Citrin-deficient patient-derived induced pluripotent stem cells as a pathological liver model for congenital urea cycle disordersMol Genet Metab Rep 2024;40:101096. [Link]
- Matsuoka Y, Nakatsuka R, Fujioka T.: Automatic Discrimination of Human Hematopoietic Tumor Cell Lines using a Combination of Imaging Flow Cytometry and Convolutional Neural Network. Human Cell 2021;34(3):1021.[Link]
- Tamaki H, Ikegame K, Yoshihara S, Kaida K, Yoshihara K, Inoue T, Kato R, Nakata J, Fujioka T, Soma T, Okada M and Ogawa H, Low incidence of HHV-6 reactivation in haploidentical hematopoietic stem cell transplantation with corticosteroid as graft-vs-host disease prophylaxis compared with cord blood transplantation, Transplant Infectious Disease:e13073, 2019
- Preprint: Matsuoka Y, Nakatsuka R, Fujioka T. Automatic Single-Cell Discrimination by Cellular Appearance using Convolutional Neural Network. bioRxiv, doi: https://doi.org/10.1101/446823
- Matsuoka Y, Nakamura F, Hatanaka K, Fujioka T, Otani S, Kimura T, Fujimura Y, Asano H and Sonoda Y, The number of CD34+CD133+ hematopoietic stem cell residing in umbilical cord blood (UCB) units is not correlated with the number of total nucreated cells and CD34+ cells: A possible new indicator for quality evaluation of UCB units., International Journal of Hematology, DOI: 10.1007/s12185-018-2502-7 ,2018
- Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y and Sonoda Y, A Rivised Road Map for the Comittment of Human Cord Blood CD34-negative Hematopoietic Stem Cells, Nature Communications, 9(1):2202,2018
- Kawamura H, Nakatsuka R, Matsuoka Y, Sumide K, Fujioka T, Asano H, Iida H and Sonoda Y, TGF-β Signaling Accelerates Senescence of Human Bone-Derived CD271 and SSEA-4 Double-Positive Mesenchymal Stromal Cells, Stem Cell Reports, 10(3):920-32,2018
- Matsuoka Y, Takahashi M, Sumide K, Kawamura H, Nakatsuka R, Fujioka T and Sonoda Y, CD34 Antigen and the MPL Receptor Expression Defines A Novel Class Of Human Cord Blood-derived Primitive Hematopoietic Stem Cells, Cell Transplant, 26(6):1043-1058,2017
- Matsuoka Y, Sumide K, Kawamura H, Nakatsuka R, Fujioka T and Sonoda Y, GPI-80 expression highly purifies human cord blood_derived primitive CD34-negative hematopoietic stem cells, Blood, 128:2258-2260, 2016
- Nakatsuka R, Iwaki R, Matsuoka Y, Sumide K, Kawamura H, Fujioka T, Sasaki Y, Uemura Y, Asano H, Kwon A-Hon, Sonoda Y: Identification and Characterization of Lineage-CD45-Sca-1+ VSEL Phenotypic Cells Residing in Adult Mouse Bone Tissue. Stem Cells Dev 25:27-42,2016
- Matsuoka Y, Sumide K, Kawamura H, Nakatsuka R, Fujioka T, Sasaki Y and Sonoda Y, Human cord blood-derived primitive CD34-negative hematopoietic stem cells (HSCs) are myeloid-biased long-term repopulating HSCs, Blood Cancer J, 5:e290, 2015
- Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, Uemura Y, Asano H, Sasaki Y, Inoue M, Ogawa H, Takahashi T, Hino M and Sonoda Y, Prospectively Isolated Human Bone marRow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells, Stem Cells, 33:1554-1565, 2015
- Kato R, Tamaki H, Ikegame K, Yoshihara S, Kaida K, Taniguchi K, Inoue T, Ishii S, Nakata J, Fujioka T, Eguchi R, Soma T, Okada and Ogawa H, Early detection of cytomegalovirus-specific cytotoxic T lymphocytes against cytomegalovirus antigenemia in human leukocyte antigen haploidentical hematopoietic stem cell transplantation, Ann Hematol, 94:1707-15, 2015
- Nakatsuka R, Matsuoka Y, Uemura Y, Sumide K, Iwaki R, Takahashi M, Fujioka T, Sasaki Y and Sonoda Y, Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro, Cell Transplant, 24:97-113, 2015
- Takahashi M, Matsuoka Y, Sumide K, Nakatsuka R, Fujioka T, Kohno H, Sasaki Y, Matsui K, Asano H, Kaneko K and Sonoda Y, CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells, Leukemia, 28(6):1308-15, 2014
- Ikegame K, Kato R, Fujioka T, Okada M, Kaida K, Ishii S, Yoshihara S, Inoue T, Taniguchi K, Tamaki H, Soma T and Ogawa H, Detection of donor-derived CMV-specific T cells in cerebrospinal fluid in a case of CMV meningoencephalitis after cord blood stem cell transplantation, Int J Hematol, 97(2):287-90, 2013
- Fujioka T, Tamaki H, Ikegame K, Yoshihara S, Taniguchi K, Kaida K, Kato R, Inoue T, Nakata J, Ishii S, Soma T, Okada M and Ogawa H, Frequency of CD4(+)FOXP3(+) regulatory T-cells at early stages after HLA-mismatched allogeneic hematopoietic SCT predicts the incidence of acute GVHD, Bone Marrow Transplant, 48(6):859-64, 2013
- Yoshihara S, Maruya E, Taniguchi K, Kaida K, Kato R, Inoue T, Fujioka T, Tamaki H, Ikegame K, Okada M, Soma T, Hayashi K, Fujii N, Onuma T, Kusunoki Y, Saji H and Ogawa H, Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT, Bone Marrow Transplant, 47(4):508-15, 2012
- Yoshihara S, Ikegame K, Taniguchi K, Kaida K, Kim E H, Nakata J, Kato R, Inoue T, Fujioka T, Tamaki H, Okada M, Soma T and Ogawa H, Salvage haploidentical transplantation for graft failure using reduced-intensity conditioning, Bone Marrow Transplant, 47(3):369-73, 2012
- Yoshihara S, Ikegame K, Kaida K, Taniguchi K, Kato R, Inoue T, Fujioka T, Tamaki H, Okada M, Soma T and Ogawa H, Incidence of extramedullary relapse after haploidentical SCT for advanced AML/myelodysplastic syndrome, Bone Marrow Transplant, 47(5):669-76, 2012
- Taniguchi K, Yoshihara S, Tamaki H, Fujimoto T, Ikegame K, Kaida K, Nakata J, Inoue T, Kato R, Fujioka T, Okada M, Soma T and Ogawa H, Incidence and treatment strategy for disseminated adenovirus disease after haploidentical stem cell transplantation, Ann Hematol, 91(8):1305-12, 2012
- Taniguchi K, Yoshihara S, Maruya E, Ikegame K, Kaida K, Hayashi K, Kato R, Inoue T, Fujioka T, Tamaki H, Okada M, Onuma T, Fujii N, Kusunoki Y, Soma T, Saji H and Ogawa H, Donor-derived HLA antibody production in patients undergoing SCT from HLA antibody-positive donors, Bone Marrow Transplant, 47(10):1338-42, 2012
- Tamaki H, Fujioka T, Ikegame K, Yoshihara S, Kaida K, Taniguchi K, Kato R, Tokugawa T, Nakata J, Inoue T, Yano A, Eguchi R, Okada M, Maruya E, Saji H and Ogawa H, Different mechanisms causing loss of mismatched human leukocyte antigens in relapsing t(6;11)(q27;q23) acute myeloid leukemia after haploidentical transplantation, Eur J Haematol, 89(6):497-500, 2012
- Ikemoto J, Yoshihara S, Fujioka T, Ohtsuka Y, Fujita N, Kokubunji A, Okamoto N, Ono J, Taniguchi K, Kaida K, Ikegame K, Okada M, Tanizawa T, Ogawa H and Kai S, Impact of the mobilization regimen and the harvesting technique on the granulocyte yield in healthy donors for granulocyte transfusion therapy, Transfusion, 52(12):2646-52, 2012
- Ikegame K, Kaida K, Yoshihara S, Fujiwara M, Taniguchi K, Kato R, Inoue T, Fujioka T, Tamaki H, Okada M, Soma T, Kamikonya N, Saji H, Hirota S and Ogawa H, Feasibility of unmanipulated haploidentical stem cell transplantation using standard GVHD prophylaxis for HLA-homozygous patients, Int J Hematol, 96(1):101-8, 2012
- Ikegame K, Yoshihara S, Taniguchi Y, Kaida K, Inoue T, Okada M, Taniguchi K, Hasei H, Tamaki H, Fujioka T, Kato R, Soma T and Ogawa H, Allogeneic stem cell transplantation as treatment for heavily treated, refractory acute graft-versus-host disease after HLA-mismatched stem cell transplantation, Exp Hematol, 39(8):880-90, 2011
- Satake A, Inoue T, Kubo S, Taniguchi Y, Imado T, Fujioka T, Horiuchi M, Xu Y, Ikegame K, Yoshihara S, Kaida K, Tamaki H, Okada M, Okamura H and Ogawa H, Separation of antileukemic effects from graft-versus-host disease in MHC-haploidentical murine bone marrow transplantation: participation of host immune cells, Int J Hematol, 91(3):485-97, 2010
- Tamaki H, Yoshihara S, Fujioka T, Kawakami M, Oka Y and Ogawa H, Molecular detection of AML1-MTG8-positive cells in peripheral blood from a patient with isolated extramedullary relapse of t(8;21) acute myeloid leukemia, Leukemia, 23(2):424-6, 2009
- Taniguchi Y, Yoshihara S, Hoshida Y, Inoue T, Fujioka T, Ikegame K, Kawakami M, Masuda T, Aozasa K, Kawase I and Ogawa H, Recovery from established graft-vs-host disease achieved by bone marrow transplantation from a third-party allogeneic donor, Exp Hematol, 36(9):1216-25, 2008
- Ogawa H, Ikegame K, Kaida K, Yoshihara S, Fujioka T, Taniguchi Y, Tamaki H, Inoue T, Hasei H, Iiboshi Y, Tazuke Y, Kawakami M, Kim E H, Soma T and Kawase I, Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) bone marrow transplantation using only pharmacological GVHD prophylaxis, Exp Hematol, 36(1):1-8, 2008
- Kaida K, Ikegame K, Fujioka T, Taniguchi Y, Inoue T, Hasei H, Tamaki H, Yoshihara S, Kawase I and Ogawa H, Kinetics of granulocyte colony-stimulating factor in the human milk of a nursing donor receiving treatment for mobilization of the peripheral blood stem cells, Acta Haematol, 118(3):176-7, 2007
- Fujiki F, Oka Y, Tsuboi A, Kawakami M, Kawakatsu M, Nakajima H, Elisseeva O A, Harada Y, Ito K, Li Z, Tatsumi N, Sakaguchi N, Fujioka T, Masuda T, Yasukawa M, Udaka K, Kawase I, Oji Y and Sugiyama H, Identification and characterization of a WT1 (Wilms Tumor Gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes, J Immunother, 30(3):282-93, 2007
- Ikegame K, Kaida K, Fujioka T, Kawakami M, Hasei H, Inoue T, Taniguchi Y, Yoshihara S, Hayashi S, Kurata Y and Ogawa H, Idiopathic thrombocytopenic purpura after influenza vaccination in a bone marrow transplantation recipient, Bone Marrow Transplant, 38(4):323-4; author reply 324-5, 2006
- Li Z, Oka Y, Tsuboi A, Masuda T, Tatsumi N, Kawakami M, Fujioka T, Sakaguchi N, Nakajima H, Fujiki F, Udaka K, Oji Y, Kawase I and Sugiyama H, WT1(235), a ninemer peptide derived from Wilms' tumor gene product, is a candidate peptide for the vaccination of HLA-A*0201-positive patients with hematopoietic malignancies, Int J Hematol, 82(5):458-9, 2005
- Ikegame K, Kawakami M, Yamagami T, Maeda H, Onishi K, Taniguchi Y, Fujioka T, Masuda T, Kawase I and Ogawa H, HLA-haploidentical nonmyeloablative stem cell transplantation: induction to tolerance without passing through mixed chimaerism, Clin Lab Haematol, 27(2):139-41, 2005
- Ogawa H, Ikegame K, Kawakami M, Tsuboi A, Kim E H, Hosen N, Murakami M, Fujioka T, Masuda T, Taniguchi Y, Yoshihara S, Tatekawa T, Oka Y, Kawase I, Soma T and Oji Y, Powerful graft-versus-leukemia effects exerted by HLA-haploidentical grafts engrafted with a reduced-intensity regimen for relapse following myeloablative HLA-matched transplantation, Transplantation, 78(3):488-9, 2004
- Kim E H, Ikegame K, Kawakami M, Nishida S, Fujioka T, Taniguchi Y, Masuda T, Oka Y, Kawase I and Ogawa H, Unmanipulated reduced-intensity stem cell transplantation from a haploidentical donor mismatched at 3 HLA antigens to a patient with leukemic transformation of myelodysplastic syndrome: successful second transplantation after graft rejection, Int J Hematol, 80(5):449-52, 2004
- Tamaki H, Mishima M, Kawakami M, Tsuboi A, Kim E H, Hosen N, Ikegame K, Murakami M, Fujioka T, Masuda T, Taniguchi Y, Nishida S, Osumi K, Soma T, Oji Y, Oka Y, Kawase I, Sugiyama H and Ogawa H, Monitoring minimal residual disease in leukemia using real-time quantitative polymerase chain reaction for Wilms tumor gene (WT1), Int J Hematol, 78(4):349-56, 2003
- Tamaki H, Ikegame K, Kawakami M, Fujioka T, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Kawase I and Ogawa H, Successful engraftment of HLA-haploidentical related transplants using nonmyeloablative conditioning with fludarabine, busulfan and anti-T-lymphocyte globulin, Leukemia, 17(10):2052-4, 2003
- Ogawa H, Tamaki H, Ikegame K, Soma T, Kawakami M, Tsuboi A, Kim E H, Hosen N, Murakami M, Fujioka T, Masuda T, Taniguchi Y, Nishida S, Oji Y, Oka Y and Sugiyama H, The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia, Blood, 101(5):1698-704, 2003
- Ikegame K, Tanji Y, Kitai N, Tamaki H, Kawakami M, Fujioka T, Oka Y, Maruya E, Saji H, Sugiyama H and Ogawa H, Successful treatment of refractory T-cell acute lymphoblastic leukemia by unmanipulated stem cell transplantation from an HLA 3-loci mismatched (haploidentical) sibling, Bone Marrow Transplant, 31(6):507-10, 2003
- Ikegame K, Mukouchi C, Kunitomi A, Konaka Y, Kawakami M, Nishida S, Taniguchi Y, Fujioka T, Masuda T, Murakami M, Hosen N, Kim E H, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Kawase I and Ogawa H, Successful treatment of bcr/abl-positive acute mixed lineage leukemia by unmanipulated bone marrow transplantation from an HLA-haploidentical (3-antigen-mismatched) cousin, Bone Marrow Transplant, 31(12):1165-8, 2003
- Fujioka T, Taniguchi Y, Masuda T, Nishida S, Ikegame K, Kawakami M, Tsuboi A, Hosen N, Murakami M, Oji Y, Oka Y, Sugiyama H, Kawase I and Ogawa H, The effect on the proliferation and apoptosis of alloreactive T cells of cell dose in a murine MHC-mismatched hematopoietic cell transplantation model, Transpl Immunol, 11(2):187-95, 2003
- Tsuboi A, Oka Y, Udaka K, Murakami M, Masuda T, Nakano A, Nakajima H, Yasukawa M, Hiraki A, Oji Y, Kawakami M, Hosen N, Fujioka T, Wu F, Taniguchi Y, Nishida S, Asada M, Ogawa H, Kawase I and Sugiyama H, Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues, Cancer Immunol Immunother, 51(11-12):614-20, 2002
- Oji Y, Miyoshi S, Maeda H, Hayashi S, Tamaki H, Nakatsuka S, Yao M, Takahashi E, Nakano Y, Hirabayashi H, Shintani Y, Oka Y, Tsuboi A, Hosen N, Asada M, Fujioka T, Murakami M, Kanato K, Motomura M, Kim E H, Kawakami M, Ikegame K, Ogawa H, Aozasa K, Kawase I and Sugiyama H, Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers, Int J Cancer, 100(3):297-303, 2002
- Ogawa H, Soma T, Hosen N, Tatekawa T, Tsuboi A, Oji Y, Tamaki H, Kawakami M, Ikegame K, Murakami M, Fujioka T, Kim E H, Oka Y and Sugiyama H, Combination of tacrolimus, methotrexate, and methylprednisolone prevents acute but not chronic graft-versus-host disease in unrelated bone marrow transplantation, Transplantation, 74(2):236-43, 2002
- Hosen N, Sonoda Y, Oji Y, Kimura T, Minamiguchi H, Tamaki H, Kawakami M, Asada M, Kanato K, Motomura M, Murakami M, Fujioka T, Masuda T, Kim E H, Tsuboi A, Oka Y, Soma T, Ogawa H and Sugiyama H, Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells, Br J Haematol, 116(2):409-20, 2002
- Ikegame K, Takimoto T, Takahashi R, Murakami M, Tamaki H, Fujioka T, Kawakami M, Hirabayashi N, Soma T, Sugiyama H and Ogawa H, Lethal adenovirus infection in a patient who had undergone nonmyeloablative stem cell transplantation, Int J Hematol, 74(1):95-100, 2001
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