研究実績(学術雑誌論文)
2023年
林 美樹夫 がん幹細胞を標的とした経口抗癌剤の開発 Medical Science Digest, 49(4):211-213
Noritake A, Nakamura K Rewarding-unrewarding prediction signals under a bivalent context in the primate lateral hypothalamus. Scientific reports, 13(1):5926
Tanaka R, Watanabe K, Suzuki T, Nakamura K, Yasuda M, Ban H, Okada K, Kitazawa S An easy-to-implement, non-invasive head restraint method for monkey fMRI NeuroImage, 285: 120479
2022年
宮内哲 生理心理学におけるパラダイム・シフト 生理心理学と精神生理学, 40(1):39-44
中村加枝, 石井宏憲, 安田正治 様々な視点から意思決定を考察する 薬理学的な視点から 精神科, 41(4):500-507
Sakaguchi T, Sumiyama F, Kotsuka M, Hatta M, Yoshida T, Hayashi M, Kaibori M, Sekimoto M. Levosimendan Increases Survival in a D-Galactosamine and Lipopolysaccharide Rat Model. Biomedicines, 10(12):3161
Kaibori M, Matsui K, Hayashi M. Theranostics Using Indocyanine Green Lactosomes. Cancers, 14(15):3840
Takanami K, Oti T, Kobayashi Y, Hasegawa K, Ito T, Tsutsui N, Ueda Y, Carstens E, Sakamoto T, Sakamoto H. Characterization of the expression of gastrin-releasing peptide and its receptor in the trigeminal and spinal somatosensory systems of Japanese macaque monkeys: Insight into humans. The Journal of comparative neurology, 530(16):2804-2819
Shoji T, Hayashi M, Sumi C, Kusunoki M, Uba T, Matsuo Y, Hirota K. Sevoflurane Does Not Promote the Colony-Forming Ability of Human Mesenchymal Glioblastoma Stem Cells In Vitro. Medicina (Kaunas, Lithuania), 58(11):1614
Kuraoka K, Nakamura K. Facial temperature and pupil size as indicators of internal state in primates. Neuroscience research, 175:25-37
Hatta M, Kaibori M, Matsushima H, Yoshida T, Okumura T, Hayashi M, Yoshii K, Todo T, Sekimoto M. Efficacy of a third-generation oncolytic herpes simplex virus in refractory soft tissue sarcoma xenograft models. Molecular therapy oncolytics, 25:225-235
2021年
Mori, K., Nakamura, K., Hashimoto, S., Wakida, M., Hase, K. Novel characterization of subjective visual vertical in patients with unilateral spatial neglect. Neurosci Res., DOI:10.1016/j.neures.2020.02.005
中村 加枝, 石井 宏憲, 安田 正治 【意思決定と行動選択の神経科学】セロトニンと意思決定 Clinical Neuroscience, 39(8):979-983
Otubo A, Maejima S, Oti T, Satoh K, Ueda Y, Morris JF, Sakamoto T, Sakamoto H. Immunoelectron Microscopic Characterization of Vasopressin-Producing Neurons in the Hypothalamo-Pituitary Axis of Non-Human Primates by Use of Formaldehyde-Fixed Tissues Stored at -25 °C for Several Years.International journal of molecular sciences, 22(17):9180
Maruyama M, Nakano Y, Nishimura T, Iwata R, Matsuda S, Hayashi M, Nakai Y, Nonaka M, Sugimoto T. PC3-secreted microprotein is expressed in glioblastoma stem-like cells and human glioma tissues. Biological & pharmaceutical bulletin, 44(7):910-919
Matsuo T, Isosaka T, Hayashi Y, Tang L, Doi A, Yasuda A, Hayashi M, Lee CY, Cao L, Kutsuna N, Matsunaga S, Matsuda T, Yao I, Setou M, Kanagawa D, Higasa K, Ikawa M, Liu Q, Kobayakawa R, Kobayakawa K. Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation. Nature communications, 12(1):2074
Saha T, Aoun J, Hayashi M, Ali SI, Sarkar P, Bag PK, Leblanc N, Ameen N, Woodward OM, Hoque KM. Intestinal TMEM16A control luminal chloride secretion in a NHERF1 dependent manner. Biochemistry and biophysics reports, 25:100912
宮内哲,寒重之 特集I Default Mode Network, Default Mode Networkと睡眠時の自発性脳活動 脳神経内科, 94(2):200-205
Ishizaki Y, Higuchi T, Yanagimoto Y, Kobayashi H, Noritake A, Nakamura K, Kaneko K Eye gaze differences in school scenes between preschool children and adolescents with high-functioning autism spectrum disorder and those with typical development. BioPsychoSocial medicine, 15(1):2-2
2020年
Otubo, A., Kawakami, N., Maejima, S., Ueda, Y., Morris, JF., Sakamoto, T., Sakamoto, H. Vasopressin gene products are colocalised with corticotrophin-releasing factor within neurosecretory vesicles in the external zone of the median eminence of the Japanese macaque monkey (Macaca fuscata) . Journal of Neuroendocrinology, 32(8):e12875
Kawakami, N., Otubo, A., Maejima, S., Talukder AH, Satoh, K., Oti, T., Takanami, K., Ueda, Y., Itoi, K., Morris JF, Sakamoto, T., Sakamoto, H. Variation of pro-vasopressin processing in parvocellular and magnocellular neurons in the paraventricular nucleus of the hypothalamus: Evidence from the vasopressin-related glycopeptide copeptin. The Journal of comparative neurology, doi:10.1002/cne.25026.
宮内 哲 【脳科学と精神療法】アンジェロ・モッソ 魂の重さを測った研究者, 精神療法, 46(4):511-513
宮内 哲, 寒 重之 睡眠と覚醒の科学(第11回) 脳機能イメージングと睡眠, 睡眠医療, 14(3):335-339
宮内 哲, 寒 重之 【睡眠障害の基礎と臨床】特論 機能的磁気共鳴画像による睡眠研究, 日本臨床, 78(増刊6 最新臨床睡眠学(第2版)):748-752
Iwata R, Lee JH, Hayashi M, Dianzani U, Ofune K, Maruyama M, Oe S, Ito T, Hashiba T, Yoshimura K, Nonaka M, Nakano Y, Norian L, Nakano I, Asai A. ICOSLG-mediated regulatory T cell expansion and IL-10 production promote progression of glioblastoma. Neuro-Oncology, 22(3):333-344
2019年
Noritake A, Nakamura K., Encoding prediction signals during appetitive and aversive Pavlovian conditioning in the primate lateral hypothalamus. Journal of neurophysiology, 121(2):396-417, 2019/02
Yasuda M, Hikosaka O., Medial thalamus in the territory of oculomotor basal ganglia represents stable object value. The European journal of neuroscience, 49(5):672-686, 2019/03
Hikosaka O, Kim HF, Amita H, Yasuda M, Isoda M, Tachibana, Y, Yoshida A, Direct and indirect pathways for choosing objects and actions. The European journal of neuroscience, 49(5):637-645, 2019/03
Nagai, Y., Nishitani, N., Yasuda, M., Ueda, Y., Fukui, Y., Andoh, C., Shirakawa, H., Nakagawa, T., Inoue, K. I., Nagayasu, K., Kasparov, S., Nakamura, K. and Kaneko, S.Identification of neuron-type specific promoters in monkey genome and their functional validation in mice. Biochem Biophys Res Commun; 518(4):619-24 (2019)
Hikosaka, O., Yasuda, M., Nakamura, K. Isoda, M. Kim, H. F. Terao, Y. Amita, H. Maeda, K.Multiple neuronal circuits for variable object-action choices based on short- and long-term memories. PNAS, 116 (52) 26313-26320 (2019)
Shoji T, Hayashi M, Sumi C, Kusunoki M, Uba T, Matsuo Y, Kimura H, Hirota K. Pharmacological polysulfide suppresses glucose-stimulated insulin secretion in an ATP-sensitive potassium channel-dependent manner. Scientific Reports, 9:19377, 2019
Kusunoki M, Hayashi M, Shoji T, Uba T, Tanaka H, Sumi C, Matsuo Y, Hirota K. Propofol inhibits stromatoxin-1-sensitive voltage-dependent K+ channels in pancreatic β-cells and enhances insulin secretion.P eerJ, 7:e8157, 2019
Hayashi M.Expression of adenosine receptors in rodent pancreas. International Journal of Molecular Sciences, 20(21):E5329, 2019
Inagaki A, Hayashi M, Andharia N, Matsuda H. Involvement of butyrate in electrogenic K+ secretion in rat rectal colon. Pflugers Archiv - European Journal of Physiology, 471(2):313-327, 2019
2018年
Ito T, Oti T, Takanami K, Satoh K, Ueda Y, Sakamoto T, Sakamoto H., A sexually dimorphic peptidergic system in the lower spinal cord controlling penile function in non-human primates. Spinal cord, 56(1):57-62, 2018/01
Andharia N, Hayashi M, Matsuda H. Electrophysiological properties of anion exchangers in the luminal membrane of guinea pig pancreatic duct cells. Pflugers Archiv - European Journal of Physiology, 470(6):897-907, 2018
Taketo M., Metabotropic glutamate receptor 1- mediated calcium mobilization in the neonatal hippocampal marginal zone. Eur J Neurosci, 48: 3344-3353 2018/12
2017年
中村加枝, 林和子, 中尾和子, 背側縫線核による報酬・嫌悪情報処理 日本薬理学雑誌, 149(1):40-43, 2017/01
Yasuda M, Hikosaka O, To Wait or Not to Wait-Separate Mechanisms in the Oculomotor Circuit of Basal Ganglia. Frontiers in Neuroanatomy, 11(35), 2017/04
Nakamura K, Ding L, Parsing Heterogeneous Striatal Activity. Frontiers in neuroanatomy, 11:43, 2017/05
Higuchi T, Ishizaki Y, Noritake A, Yanagimoto Y, Kobayashi H, Nakamura K, Kaneko K, Spatiotemporal characteristics of gaze of children with autism spectrum disorders while looking at classroom scenes. PLoS ONE, 12(5):e0175912, 2017/05
Ueda Y, Yamanaka K, Noritake A, Enomoto K, Matsumoto N, Yamada H, Samejima K, Inokawa H, Hori Y, Nakamura K, Kimura M, Distinct Functions of the Primate Putamen Direct and Indirect Pathways in Adaptive Outcome-Based Action Selection. frontiers in Neuroanatomy, 11:Article 66, 2017/08
Wong-Lin K, Wang DH, Moustafa AA, Cohen JY, Nakamura K, Toward a multiscale modeling framework for understanding serotonergic function. the Journal of Psychopharmacology, 31(9):1121-1136, 2017/09
Andharia N, Joseph A, Hayashi M, Okada M, Matsuda H. Involvement of intracellular transport in TREK-1c current run-up in 293T cells. Channels (Austin), 11(3):224-235, 2017
Taketo M., Matsuda H., Short-term inhibition of GABAergic IPSCs induced by association of pre- and postsynaptic activation in the neonatal hippocampus. Neuropharmacology, 121:39-48 2017/07
2016年
McCairn KW, Nagai Y, Hori Y, Ninomiya T, Kikuchi E, Lee JY, Suhara T, Iriki A, Minamimoto T, Takada M, Isoda M, Matsumoto M, A primary role for nucleus accumbens and related limbic network in vocal tics. Neuron, 89(2):300-307, 2016/01
樋口隆弘, 則武厚, 石崎優子, 柳本嘉時, 小林穂高, 金子一成, 思春期高機能自閉症スペクトラム障害児の視線解析 定型発達児との視線滞留対象の比較 子どもの心とからだ, 24(4):467-469, 2016/02
Yamada H, Inokawa H, Hori Y, Pan X, Matsuzaki R, Nakamura K, Samejima K, Shidara M, Kimura M, Sakagami M, Minamimoto T, Characteristics of fast-spiking neurons in the striatum of behaving monkeys. Neurosci Res, 105:2-18, 2016/04
Yoshida K, Go Y, Kushima I, Toyoda A, Fujiyama A, Imai H, Saito N, Iriki A, Ozaki N, Isoda M., Single-neuron and genetic correlates of autistic behavior in macaque. Science advances, 2(9):e1600558, 2016/09
Aoun J, Hayashi M, Sheikh IA, Sarkar P, Saha T, Ghosh P, Bhowmick R, Ghosh D, Chatterjee T, Chakrabarti P, Chakrabarti MK, Hoque KM. Anoctamin 6 Contributes to Cl- Secretion in Accessory Cholera Enterotoxin (Ace)-stimulated Diarrhea: An Essential Role for Phosphatidylinositol 4,5-bisphosphate (PIP2) Signaling in Cholera. The Journal of Biological Chemistry, 291(52):26816-26836, 2016
Hayashi M, Inagaki A, Novak I, Matsuda H. The adenosine A2B receptor is involved in anion secretion in human pancreatic duct Capan-1 epithelial cells. Pflugers Archiv - European Journal of Physiology, 468(7):1171-1181, 2016
2015年
Burton AC, Nakamura K, Roesch MR , From ventral-medial to dorsal-lateral striatum: Neural correlates of reward-guided decision-making. Neurobiology of learning and memory, 117:51-59 , 2015/01
磯田昌岐, 神経科学 ニホンザルの神経生理 自己の動作と他者の動作を区別する神経回路 Clinical Neuroscience, 33(2):147-150, 2015/02
則武厚, 磯田昌岐, 社会的階層と集団サイズ 生体の科学 , 66(1):72-75 , 2015/02
磯田昌岐, 神経心理学への多面的アプローチ 社会的認知機能の生理学的理解 サルを用いた研究から 神経心理学, 31(1):17-25, 2015/03
Yasuda M, Hikosaka O, Functional territories in primate substantia nigra pars reticulata separately signaling stable and flexible values. Journal of neurophysiology, 113(6):1681-1696 , 2015/03
Hayashi K, Nakao K, Nakamura K, Appetitive and aversive information coding in the primate dorsal raphe' nucleus. The Journal of neuroscience, 35(15):6195-6208, 2015/04
McCairn KW, Iriki A, Isoda M, Common therapeutic mechanisms of pallidal deep brain stimulation for hypo- and hyperkinetic movement disorders. Journal of neurophysiology, 114(4):2090-2104, 2015/10
2014年
中村加枝, 林和子, 則武厚, 意思決定・行動選択の神経科学 セロトニンと意思決定 Clinical Neuroscience, 32(1):55-57, 2014/01
Nakamura K, Wong-Lin K, Functions and computational principles of serotonergic and related systems at multiple scales. Frontiers in integrative neuroscience, 8:Article No. 23, 2014/03
Chang SW, Isoda M, Toward a better understanding of social learning, social deciding, and other-regarding preferences. Frontiers in neuroscience, 8:Article No. 362, 2014/11
Namima T, Yasuda M, Banno T, Okazawa G, Komatsu H, Effects of luminance contrast on the color selectivity of neurons in the macaque area v4 and inferior temporal cortex. The Journal of neuroscience, 34(45):14934-14947, 2014/11
2013年
Isoda M, Noritake A, What makes the dorsomedial frontal cortex active during reading the mental states of others? Frontiers in neuroscience, 7: Article No. 232, 2013
McCairn KW, Isoda M, Pharmacological Animal Models of Tic Disorders. International review of neurobiology, 112:179-209, 2013
Nakamura K, The role of the dorsal raphe nucleus in reward-seeking behavior. Frontiers in integrative neuroscience, 7:60, 2013
Isoda M, Recent advances in social neuroscience research using macaques. Brain Nerve, 65(6):679-686, 2013
Isosa M, Using saccades as a probe of higher brain functions. Neuro Ophthalmology Japan, 30(1), 2013
McCairn KW, Iriki A, Isoda M, Deep brain stimulation reduces Tic-related neural activity via temporal locking with stimulus pulses. J Neurosci, 33(15):6581-93, 2013
McCairn KW, Iriki A, Isoda M, Global dysrhythmia of cerebro-basal ganglia-cerebellar networks underlies motor tics following striatal disinhibition. J Neurosci, 33(2):697-708, 2013
Yamada H, Inokawa H, Matsumoto N, Ueda Y, Enomoto K, Kimura M, Coding of the long-term value of multiple future rewards in the primate striatum. J Neurophysiol, 109(4):1140-51, 2013
Hayashi M, Novak I.Molecular basis of potassium channels in pancreatic duct epithelial cells.Channels (Austin), 7(6): 432-441, 2013
2012年
Nakamura K, Santos G, Matsuzaki R, Nakahara H, Differential reward coding in the subdivisions of the primate caudate during an oculomotor task. J Neurosci, 32 (45):15963-15982, 2012
Yoshida K, Saito N, Iriki A, Isoda M, Social error monitoring in macaque frontal cortex. Nature Neuroscience, 15(9):1307-1312, 2012
Hayashi M, Wang J, Hede SE, Novak I.An intermediate-conductance Ca2+-activated K+ channel is important for secretion in pancreatic duct cells.American Journal of Physiology. Cell Physiology 303(2):C151-C159, 2012
2011年
Okada K, Nakamura K, Kobayashi Y, A neural correlate of predicted and actual reward-value information in monkey pedunculopontine tegmental and dorsal raphe nucleus during saccade tasks. Neural Plast, 2011:579840, 2011
Cools R, Nakamura K, Daw ND, Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology, 36:98-113, 2011
2010年
Yoshizawa K, Nakao K, Habiro M, Hayashi K, Kuwata M, Uehara N, Yuri T, Nakamura K, Tsubura A, Cerebromalacia with epilepsy and cortical blindness in a laboratory Japanese macaque (Macaca fuscata). Toxicol Pathol, 38:1058-1063, 2010
Bromberg-Martin ES, Hikosaka O, Nakamura K, Coding of task reward value in the dorsal raphe nucleus. J Neurosci, 30:6262-6272, 2010
Matsuda H, Hayashi M, Okada M.Voltage-dependent block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1, with asymmetrical K+ concentrations.The Journal of Physiology, 588(Pt 23):4673-4681, 2010
Taketo M., Matsuda H., Modulation of intracellular calcium mobilization and GABAergic currents through subtype-specific metabotropic glutamate receptors in neonatal rat hippocampus. Brain Res Bull, 81: 73-80 2010/01
2009年
Ichikawa J, Gemba H, Cell density-dependent changes in intracellular Ca2+ mobilization via the P2Y2 receptor in rat bone marrow stromal cells. J Cell Physiol, 219:372-381, 2009
2008年
Nakamura K, Matsumoto M, Hikosaka O, Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus. J Neurosci, 28:5331-5343, 2008
Kyuhou S, Preventive effects of genistein on motor dysfunction following 6-hydroxydopamine injection in ovariectomized rats. Neurosci Lett, 448:10-14, 2008
2007年
Kyuhou S, Gemba H, Fast cortical oscillation after thalamic degeneration: pivotal role of NMDA receptor. Biochem Biophys Res Commun, 356:187-192, 2007
Gemba H, Cortical field potentials and cognitive functions. In: Complex Medical Engineering (Wu JL, Ito K, Tobimatsu S, Nishida T, Fukuyama H eds), Springer, Tokyo, 446-458, 2007
Hayashi M, Matsuda H.Negatively charged residues located near the external entrance are required for the Kir2.1 channel to function.Pflugers Archiv ? European Journal of Physiology, 455(3):455-464, 2007
2006年
Nakamura K, Hikosaka O, Facilitation of saccadic eye movements by postsaccadic electrical stimulation in the primate caudate. J Neurosci, 26:12885-12895, 2006
Nakahara H, Nakamura K, Hikosaka O, Extended LATER model can account for trial-by-trial variability of both pre- and post-processes. Neural Netw, 19:1027-1046, 2006
Nakamura K, Hikosaka O, Role of dopamine in the primate caudate nucleus in reward modulation of saccades. J Neurosci, 26:5360-5369, 2006
Hikosaka O, Nakamura K, Nakahara H, Basal ganglia orient eyes to reward. J Neurophysiol, 95:567-584, 2006
Kyuhou S, Kato N, Gemba H, Emergence of endoplasmic reticulum stress and activated microglia in Purkinje cell degeneration mice. Neurosci Lett, 396:91-96, 2006
2005年
Nakamura K, Roesch MR, Olson CR, Neuronal activity in macaque SEF and ACC during performance of tasks involving conflict. J Neurophysiol, 93:884-908, 2005
Seki T, Gemba H, Matsuzaki R, Nakao K, Readiness potential and movement initiation in the rat. Jpn J Physiol, 55:1-9, 2005
Gemba H, Nakao K, Matsuzaki R, Kyuhou S, The process from internal stimulus to movement initiation. Current Trends in Neurology, 1:109-123, 2005
2004年
Sakai K, Hikosaka O, Nakamura K, Emergence of rhythm during motor learning. Trends Cogn Sci, 8:547-53, 2004
Matsuzaki R, Kyuhou S, Matsuura-Nakao K, Gemba H, Thalamo-cortical projections to the posterior parietal cortex in the monkey. Neurosci Lett, 355:113-116, 2004
Gemba H, Matsuura-Nakao K, Matsuzaki R, Preparative activities in posterior parietal cortex for self-paced movement in monkeys. Neurosci Lett, 357:68-72, 2004
Taketo M., Matsuda H., Yoshioka T., Calcium-independent inhibition of GABAA current by caffeine in hippocampal slices. Brain Res, 1016: 229-239 2004/08
2003年
Ohishi H, Ichikawa J, Matsuzaki R, Kyuhou S, Matsuura-Nakao K, Seki T, Gemba H, Cortical field potentials preceding self-paced forelimb movements and influences of cerebellectomy upon them in rats. Neurosci Lett, 352:5-8, 2003
Kyuhou S, Matsuzaki R, Gemba H, Perirhinal cortex relays auditory information to the frontal motor cortices in the rat. Neurosci Lett, 353:181-184, 2003
2002年
Hikosaka O, Rand MK, Nakamura K, Miyachi S, Kitaguchi K, Sakai K, Lu X, Shimo Y, Long-term retention of motor skill in macaque monkeys and humans. Exp Brain Res, 147:494-504, 2002
Nakamura K, Colby CL, Updating of the visual representation in monkey striate and extrastriate cortex during saccades. Proc Natl Acad Sci U S A, 99:4026-4031, 2002
Hikosaka O, Nakamura K, Sakai K, Nakahara H, Central mechanisms of motor skill learning. Curr Opin Neurobiol, 12:217-222, 2002
Kyuhou S, Gemba H, Projection from the perirhinal cortex to the frontal motor cortex in the rat. Brain Res, 929:101-104, 2002
Gemba H, Motor programming for hand and vocalizing movements. In: Principles of Frontal Lobe Function (Stuss DT, Knight RT eds), Oxford University Press, London, 127-148, 2002
Gemba H, Kyuhou S, Matsuzaki R, Amino Y, Monkey vocalization and cortical field potential. In: Recent Advances in Human Brain Mapping (Hirata K ed), Elsevier, Amsterdam, 29-33, 2002
2001年
Shibata R, Mulder AB, Trullier O, Wiener SI, Position sensitivity in phasically discharging nucleus accumbens neurons of rats alternating between beacon approach and place navigation tasks. Neuroscience, 108:391-411, 2001
Adachi Y, Kohdera U, Sugiura K, Shinohara A, Inaba M, Ikebukuro K, Oyaizu H, Gemba H, Kobayashi Y, Ikehara S, A 4-month-old infant showing anemia, granulocytopenia and thrombocytopenia probably due to autoreactive IgG. Pediat Internat, 43:91-94, 2001
Amino Y, Kyuhou S, Matsuzaki R, Gemba H, Cerebello-thalamo-cortical projections to the posterior parietal cortex in the macaque monkey. Neurosci Lett, 309:29-32, 2001
2000年
Nakamura K, Colby CL, Visual, saccade related, and cognitive activation of single neurons in monkey extrastriate area V3A. J Neurophysiol, 84:677-692, 2000
Rand MK, Hikosaka O, Miyachi S, Lu X, Nakamura K, Kitaguchi K, Shimo Y, Characteristics of sequential movements during early learning period in monkeys. Exp Brain Res, 131:293-304, 2000
Yoshimura H, Kato N, Diverse roles of intracellular cAMP in early synaptic modifications in the rat visual cortex. J Physiol, 522:417-426, 2000
Kyuhou S, Sasaki K, Nambu A, Matsuzaki R, Tsujimoto T, Gemba H, Magnetoencephalographic study on cerebral cortical activities related to speech. In: Biomag 96 (Aine CJ, Okada Y, Stroink G, Swithenby SJ, Wood CC eds), Springer, New York, Berlin, 821-824, 2000