関西医科大学iPS・幹細胞再生医学講座

教室員

HOME教室員 > 中塚 隆介
中塚 隆介
助教
中塚 隆介
Ryusuke Nakatsuka
学歴
  • 平成14年 鳥取大学医学部生命科学科 卒業
  • 平成16年 鳥取大学大学院医学系研究科生命科学系専攻
          博士前期課程 修了
  • 平成19年 鳥取大学大学院医学系研究科生命科学専攻
          博士後期課程 修了
職歴
  • 平成19年 大阪歯科大学 薬理学講座 助教
  • 平成20年 関西医科大学院 医学研究科先端医療学専攻
          修復医療応用系 幹細胞生物学 助教
  • 平成30年 関西医科大学医学部 iPS・幹細胞再生医学講座 助教
学位
(取得大学、年)
博士(生命科学) (鳥取大学 平成19年)
E-mail nakatsur(at)hirakata.kmu.ac.jp  ((at)を@にしてください)
研究テーマ 幹細胞生物学
研究のキーワード 体性幹細胞、組織幹細胞
主要業績
  • Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y and Sonoda Y, A Rivised Road Map for the Comittment of Human Cord Blood CD34-negative Hematopoietic Stem Cells, Nature Communications, in press
  • Kawamura H, Nakatsuka R, Matsuoka Y, Sumide K, Fujioka T, Asano H, Iida H and Sonoda Y, TGF-β Signaling Accelerates Senescence of Human Bone-Derived CD271 and SSEA-4 Double-Positive Mesenchymal Stromal Cells, Stem Cell Reports, 10(3):920-32,2018
  • Matsuoka Y, Takahashi M, Sumide K, Kawamura H, Nakatsuka R, Fujioka T, Sonoda Y: CD34 Antigen and the MPL Receptor Expression Defines A Novel Class Of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells. Cell Transplant 26(6):1043-1058,2017.
  • Matsuoka Y, Sumide K, Kawamura H, Nakatsuka R, Fujioka T, Sonoda Y: GPI-80 Expression Highly Purifies Human Cord Blood-Derived Primitive CD34-Negative Hematopoietic Stem Cells. Blood 128:2258-2260, 2016.
  • Nakatsuka R, Iwaki R, Matsuoka Y, Sumide K, Kawamura H, Fujioka T, Sasaki Y, Uemura Y, Asano H, Kwon A-Hon, Sonoda Y: Identification and Characterization of Lineage-CD45-Sca-1+ VSEL Phenotypic Cells Residing in Adult Mouse Bone Tissue. Stem Cells Dev 25:27-42,2016.
  • Matsuoka Y, Sumide K, Kawamura H, Nakatsuka R, Fujioka T, Sasaki Y, Sonoda Y. Human cord blood-derived primitive CD34-negative hematopoietic stem cells (HSCs) are myeloid-biased long-term repopulating HSCs. Blood Cancer J, 5:e290, 2015.
  • Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, Uemura Y, Asano H, Sasaki Y, Inoue M, Ogawa H, Takahashi T, Hino M, Sonoda Y. Prospectively isolated human bone marrow cell-derived MSCs support primitive human CD34-negative hematopoietic stem cells. Stem Cells, 33:1554-1565, 2015.
  • Zhang R, Liu T, Senju S, Haruta M, Hirosawa N, Suzuki M, Tatsumi M, Ueda N, Maki H, Nakatsuka R, Matsuoka Y, Sasaki Y, Tsuzuki S, Nakanishi H, Araki R, Abe M, Akatsuka Y, Sakamoto Y, Sonoda Y, Nishimura Y, Kuzushima K, Uemura Y. Generation of mouse pluripotent stem cell-derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells. Cancer Immunol Res, 3:668-677, 2015.
  • Nakatsuka R, Matsuoka Y, Uemura Y, Sumide K., Iwaki R, Takahashi M, Fujioka T, Sasaki Y, Sonoda Y. Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro. Cell Transplant, 24:97-113, 2015.
  • Takahashi M, Matsuoka Y, Sumide K, Nakatsuka R, FujiokaT, Kohno H, Sasaki Y, Matsui K, Asano H, Kaneko K, Sonoda Y. CD133 is a Positive Marker for a Distinct Class of Primitive Human Cord Blood-derived CD34–negative Hematopoietic Stem Cells. Leukemia, 28:1308-1315, 2014.
  • Matsuoka, Y., Sasaki, Y., Nakatsuka, R., Takahashi, M., Iwaki, R., Uemura, Y., Sonoda, Y. Low Level of c-Kit Expression Marks Deeply Quiescent Murine Hematopoietic Stem Cells. Stem Cells, 29(11):1783-1791. 2011.
  • Kimura, T., Kohno, H., Matsuoka, Y., Nakatsuka, R., Sasaki, Y., Fukuhara, S., Sonoda, Y. CD16 antigen is a positive marker of peripheral blood-derived early endothelial progenitor cells. Int J Hematol., 2011(1):123-125. 2011.
  • Ishii, M., Matsuoka, Y., Sasaki, Y., Nakatsuka, R., Takahashi, M., Nakamoto, T., Yasuda, K., Matsui, K., Asano, H., Uemura, Y., Tsuji, T., Fukuhara, S., Sonoda, Y. Development of a High Resolution Purification Method for Precise Functional Characterization of Primitive Human Cord Blood-derived CD34-negative SCID-repopulating Cells. Exp Hematol., 39(2):203-213. 2011.
  • Kimura, T., Kohno, H., Matsuoka, Y., Murakami, M., Nakatsuka, R., Hase, M., Yasuda, K., Uemura, Y., Sasaki, Y., Fukuhara, S., Sonoda, Y. CXCL8 enhances the angiogenic activity of umbilical cord blood-derived outgrowth endothelial cells in vitro. Cell Biol Int., 35(3):201-208. 2011.
  • Nakatsuka, R., Nozaki, T., Shinohara, M., Ohura, K. Dilazep Decreases Lipopolysaccharide-Induced Nitric Oxide and TNF-α Synthesis in RAW 264 Cells. J Pharmacol Sci., 113(3):271-275. 2010.
  • Nakatsuka, R., Nozaki, T., Uemura, Y., Matsuoka, Y., Sasaki, Y., Shinohara, M., Ohura, K., Sonoda, Y. 5-Aza-2’-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells. Arch Oral Biol., 55:350-357.2010.
  • Kimura, T., Matsuoka, Y., Murakami, M., Kimura, T., Takahashi, M., Nakamoto, T., Yasuda, K., Matsui, K., Kobayashi, K., Imai, S., Asano, H., Nakatsuka, R., Uemura, Y., Sasaki, Y., Sonoda, Y. In vivo dynamics of human cord blood-derived CD34(-) SCID-repopulating cells using intra-bone marrow injection. Leukemia, 24(1):162-168. 2010.
  • Sasaki, Y., Matsuoka, Y., Hase, M., Toyohara, T., Murakami, M., Takahashi, M., Nakatsuka, R., Uemura, Y., Sonoda, Y. Marginal expression of CXCR4 on c-kit(+)Sca-1(+)Lineage(-) hematopoietic stem/progenitor cells. Int J Hematol., 90(5):553–560. 2009.
  • Uemura, Y., Liu, TY., Narita, Y., Suzuki, M., Nakatsuka, R., Araki, T., Matsumoto, M., Iwai, LK., Hirosawa, N., Matsuoka, Y., Murakami, M., Kimura, T., Hase, M., Kohno, H., Sasaki, Y., Ichihara, Y., Ishihara, O., Kikuchi, H., Sakamoto, Y., Jiao, SC., Senju, S., Sonoda, Y. Cytokine-dependent modification of IL-12p70 and IL-23 balance in dendritic cells by ligand activation of Va24 invariant natural killer T cells. J Immunol., 183(1):201-208. 2009.
  • Nakatsuka, R., Taniguchi, M., Hirata, M., Shiota, G., Sato, K. Transient expression of bone morphogenic protein-2 in acute liver injury by carbon tetrachloride. J Biochem., 141(1):113-119. 2007.
  • Taniguchi, M., Takeuchi, T., Nakatsuka, R., Watanabe, T., Sato, K. Molecular process in acute liver injury and regeneration induced by carbon tetrachloride. Life Sciences, 75(13): 1539-1549. 2004.
加入学会
  • 日本再生医療学会
  • 日本分子生物学会
  • 歯科基礎医学会
更新日 2018年6月1日

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